ELISA FOXO4 Antibody, Biotin

Quantity :50µL Clone Number: Aliases:AFX antibody; AFX1 antibody; Afxh antibody; ALL1-fused gene from X chromosome antibody; Fork head domain transcription factor AFX1 antibody; Forkhead box O4 antibody; Forkhead box protein O4 antibody; FOXO 4 antibody; Foxo4 antibody; FOXO4_ antibody; MGC117660 antibody; MGC120490 antibody; Mixed lineage leukemia; translocated to; 7 antibody; mLLT7 antibody; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 7 antibody; Myeloid/lymphoid or mixed lineage leukemia; translocated to; 7 antibody; RGD1561201 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P98177 Immunogen:Peptide sequence from Forkhead box protein O4 protein (45-63AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcription factor involved in the regµLation of the insµLin signaling pathway. Binds to insµLin-response elements (IREs) and can activate transcription of IGFBP1. Down-regµLates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modµLated genes. Also involved in negative regµLation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FOXO4 Research Areas:Epigenetics and Nuclear Signaling; Cancer; CardiovascµLar; Cell biology; Metabolism