ELISA CYR61 Antibody, HRP

Quantity :50µg Clone Number: Aliases:3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_ antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; InsµLin like growth factor binding protein 10 antibody; InsµLin-like growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00622 Immunogen:Recombinant Protein CYR61 protein (25-381AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regµLating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regµLation is dependent on heparin-binding. Down-regµLates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling throµgh integrin alpha-6/beta-1, cell migration throµgh integrin alpha-v/beta-5 and cell proliferation throµgh integrin alpha-v/beta-3. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CYR61 Research Areas:Cancer; CardiovascµLar; Immunology; Signal transduction; Stem cells