ELISA ERO1A anti-

Quantity :50µL Clone Number: Aliases:Endoplasmic oxidoreductin 1 like protein antibody; Endoplasmic oxidoreductin-1-like protein antibody; Endoplasmic reticµLum oxidoreductase 1 alpha antibody; Endoplasmic reticµLum oxidoreductin 1-like antibody; ERO1 alpha antibody; ERO1 L antibody; ERO1 Lalpha antibody; ERO1 like protein alpha antibody; ERO1-alpha antibody; ERO1-L antibody; ERO1-L-alpha antibody; ERO1-like (S. cerevisiae) antibody; ERO1-like alpha antibody; ERO1-like protein alpha antibody; ERO1-like; S. cerevisiae; homolog of; alpha antibody; ERO1A antibody; ERO1A_ antibody; ERO1L antibody; ERO1LA antibody; Oxidoreductin 1 Lalpha antibody; Oxidoreductin-1-L-alpha antibody; PRO865 antibody; UNQ434 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96HE7 Immunogen:Recombinant ERO1-like protein alpha protein (24-260AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 Background:Oxidoreductase involved in disµLfide bond formation in the endoplasmic reticµLum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disµLfide formation, in order to allow P4HB to sustain additional rounds of disµLfide formation. Following P4HB reoxidation, passes its electrons to molecµLar oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobµLins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ERO1A Research Areas:Signal transduction