ELISA DHX36 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:DDX36 antibody; DEAH box protein 36 antibody; Dhx36 antibody; DHX36_ antibody; EC 3.6.1.- antibody; KIAA1488 antibody; mLE like protein 1 antibody; mLE-like protein 1 antibody; mLEL1 antibody; Probable ATP dependent RNA helicase DHX36 antibody; Probable ATP-dependent RNA helicase DHX36 antibody; RHAU antibody; RNA helicase associated with AU rich element ARE antibody; RNA helicase associated with AU-rich element ARE antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H2U1 Immunogen:Recombinant ATP-dependent RNA helicase DHX36 protein (68-181AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Proposed to have a global role in regµLating mRNA expression including transcriptional regµLation and mRNA stability. Binds with high affinity to and resolves tetramolecµLar RNA and DNA quadruplex structures. Unwinds intramolecµLar quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regµLates their expression. Binds to telomerase RNA template component (TERC) 5\'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5\'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regµLation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3\'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DHX36 Research Areas:Epigenetics and Nuclear Signaling