ELISA CLEC4E Antibody, FITC

Quantity :50µg Clone Number: Aliases:C type lectin domain family 4 member E antibody; C type lectin superfamily member 9 antibody; C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody; C-type lectin domain family 4 member E antibody; C-type lectin superfamily member 9 antibody; CLC4E_ antibody; CLEC 4E antibody; Clec4e antibody; CLECSF9 antibody; Macrophage inducible C type lectin antibody; Macrophage-inducible C-type lectin antibody; MINCLE antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9µLY5 Immunogen:Recombinant C-type lectin domain family 4 member E protein (41-219AA) Raised in:Rabbit Reactivity: Tested Applications: Background:C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6\\\'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals throµgh an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines throµgh a pathway that depends on SYK, CARD9 and NF-kappa-B. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CLEC4E Research Areas:Immunology