Skip to Content

Electrophoresis

Revolutionizing DNA Analysis with DNA Electrophoresis Systems

The Role of Electrophoresis in DNA Analysis

Electrophoresis is one of the foundational techniques used in molecular biology for separating nucleic acids and proteins based on their size, charge, and other physical properties. It plays a crucial role in DNA analysis, gene expression studies, and many applications in clinical diagnostics, research, and biotechnology.

In recent years, technological advancements have enhanced electrophoresis methods, offering more precise, reliable, and efficient results. ATTO’s DNA Electrophoresis System is a prime example of such innovation. This system not only increases throughput and sensitivity but also ensures that researchers and clinicians have access to real-time data with minimal error, making it a vital tool in the laboratory.

What is Electrophoresis ?

Electrophoresis is a laboratory technique used to separate charged molecules, such as DNA, RNA, and proteins, through a gel matrix under the influence of an electric field. The molecules move at different speeds based on their size and charge. Smaller molecules generally migrate faster, while larger ones move more slowly.

Applications of Electrophoresis in DNA Analysis

Electrophoresis has become an indispensable technique for a variety of applications, including:

  1. Gene Mapping and Sequencing: It helps in isolating specific DNA fragments for sequencing and further analysis.
  2. PCR Analysis: After PCR amplification, electrophoresis can be used to confirm the presence of the targeted DNA fragment.
  3. Genetic Fingerprinting: This is crucial in forensics, paternity testing, and genetic disease analysis.
  4. Mutation Detection: Electrophoresis is used to detect mutations by comparing the mobility of DNA fragments before and after mutation.

How Our DNA Electrophoresis Systems Enhance DNA Analysis

The  DNA Electrophoresis System provides researchers with a more efficient, sensitive, and reliable method for analyzing DNA samples, with several key features that make it stand out :

  1. High-Throughput Capabilities
     Unlike traditional electrophoresis systems, the system supports high-throughput workflows, allowing for the simultaneous analysis of multiple samples. This is especially beneficial for large-scale research projects, clinical testing, and any laboratory that requires the processing of a significant number of samples within a short time.
  2. Real-Time Data Monitoring
    The system enables real-time monitoring of electrophoresis results, ensuring that researchers can observe the separation process as it happens. This feature allows for quicker troubleshooting and ensures high-quality results from start to finish.
  3. Enhanced Sensitivity
    The system features cutting-edge detection mechanisms that can identify even the faintest signals. This makes it ideal for low-concentration DNA analysis, ensuring that small or degraded DNA fragments can be successfully detected and analyzed.
  4. Automated and Efficient
    The system streamlines the electrophoresis process, with automated sample loading, running, and data analysis, which reduces human error and increases the consistency of results. This automation is particularly helpful in high-throughput environments.
  5. Compact Design for Small Laboratories
    Designed for ease of use, DNA electrophoresis system is compact and can be used in smaller laboratory spaces. This makes it an excellent choice for academic institutions, research labs, and clinical settings with limited space.

Electrophoresis: A Vital Tool in the World of Genomics

Electrophoresis remains one of the most versatile techniques in genomics and molecular biology. Its applications range from DNA sequencing and genetic analysis to clinical diagnostics. Our DNA Electrophoresis System enhances these capabilities by providing real-time results, high-throughput processing, and superior sensitivity, making it the ideal tool for researchers and clinicians looking for reliable results.

Why Choose Our DNA Electrophoresis for Your Laboratory?

  1. Reliability: Our system is built with the latest technology to ensure consistent, reproducible results every time.
  2. Ease of Use: Its user-friendly design and automated features make it accessible for both novice and experienced researchers.
  3. Enhanced Performance: Our system ensures faster analysis with high resolution and sensitivity, improving research timelines and outcomes.
  4. Cost-Efficiency: With high throughput and reliability, it offers significant savings in time and resources, making it an excellent investment for any lab.

Examples of DNA Electrophoresis Systems

1. WSE-1710 Submerge-Mini

The WSE-1710 Submerge-Mini is a compact agarose gel electrophoresis system designed for small-scale DNA analysis. It's ideal for educational purposes, small laboratories, and routine PCR fragment analysis.

Key Features:

  • Voltage Settings: Offers selectable constant voltages of 50V, 100V, and 150V.
  • Timer Function: Built-in timer with settings from 0 to 99 minutes, including an alarm for completion.
  • Gel Tray Sizes: Compatible with small (54×60 mm) and large (110×60 mm) gel trays.
  • Comb Options: Includes 3 mm and 5.8 mm double-edged combs, suitable for multi-channel pipetting.
  • Safety Features: Equipped with an open cover error alarm (E1) for user safety.

Applications:

  • Ideal for routine PCR product analysis.
  • Suitable for educational demonstrations and small-scale DNA separations.

2. WSE-1720 Submerge-Multi

The WSE-1720 Submerge-Multi is a versatile electrophoresis system designed for medium to high-throughput applications. It accommodates various gel sizes and is suitable for laboratories requiring flexibility and efficiency.

Key Features:

  • Voltage Settings: Provides constant voltages ranging from 18V to 135V, including intermediate steps (25V, 35V, 50V, 70V, 100V).
  • Timer Function: Timer settings up to 99 hours and 59 minutes, with an alarm feature.
  • Gel Tray Sizes: Supports gel trays of 60×60 mm, 120×60 mm, and 120×120 mm.
  • Comb Options: Comes with multiple combs (25/18/13 wells, 11/8/6/3/2 wells) to accommodate different sample volumes.
  • Safety Features: No current flows when the lid is opened, ensuring user safety.


Applications:

  • Suitable for routine DNA analysis and PCR fragment separations.
  • Ideal for laboratories requiring flexibility in gel sizes and sample volumes.

3. AE-6111 Submerge

The AE-6111 Submerge is an advanced electrophoresis system featuring buffer recirculation for enhanced separation efficiency. It's designed for high-resolution DNA analysis and is suitable for research applications.

Key Features:

  • Gel Size: Accommodates gels up to 120×160 mm with a thickness of up to 8 mm.
  • Comb Options: Includes 26-well and 13-well double-tooth combs, with well widths of 3 mm and 6 mm.
  • Buffer Volume: Supports buffer volumes ranging from 700 to 1,200 mL, depending on gel thickness.
  • Buffer Recirculation: Allows connection to an external circulator for maintaining optimal buffer conditions.
  • Material: Constructed from UV-transmissive hard acrylic, ensuring durability and clarity.

Applications:

  • High-resolution DNA separations and analysis.
  • Suitable for research laboratories requiring precise and efficient electrophoresis.

____________________________________________________________________

Choosing the Right System for Your Laboratory

Selecting the appropriate electrophoresis system depends on your laboratory's specific needs:

  • WSE-1710 Submerge-Mini: Best suited for small-scale analyses and educational purposes.
  • WSE-1720 Submerge-Multi: Ideal for laboratories requiring flexibility and medium to high-throughput capabilities.
  • AE-6111 Submerge: Designed for high-resolution separations in research settings.

Contact Us ! [email protected]