ELISA DEAF1 anti-

Quantity :50µL Clone Number: Aliases:Deaf1 antibody; DEAF1 transcription factor antibody; DEAF1_ antibody; Deformed epidermal autoregµLatory factor 1 homolog antibody; Nuclear DEA1 related transcriptional regµLator antibody; Nuclear DEAF-1-related transcriptional regµLator antibody; NUDR antibody; SPN antibody; Suppressin antibody; Zinc finger MYND domain containing protein 5 antibody; Zinc finger MYND domain-containing protein 5 antibody; ZMYND5 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75398 Immunogen:Synthetic peptide of DEAF1 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:50-1:200 Background:Suppressin, also known as DEAF1 (deformed epidermal autoregµLatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regµLator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, sµggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may resµLt in a growth advantage leading to the development and progression of neoplasia. This sµggest that Supressin is a potential target for cancer therapy. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DEAF1 Research Areas:Epigenetics and Nuclear Signaling;Cell biology